HUMAN GENETICS PROGRAM (HGP)A
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- Alter, Blanche P., M.D., M.P.H.
Study of inherited bone marrow failure syndromes. Using Fanconi's anemia as the prototype for an interdisciplinary approach to elucidate the mechanisms of carcinogenesis in humans.
- Amundadottir, Laufey, Ph.D.
gene mapping, functional analyses, pancreatic cancer,
- Brown, Kevin, Ph.D.
Melanoma, genome-wide association studies, familial linkage studies, RNAi, cancer therapeutics.
- Caporaso, Neil E., M.D.
Molecular epidemiology of lung and other tobacco-related cancers. Family studies of lympho-proliferative cancers, i.e., chronic lymphocytic leukemia. Pharmacogenetics of genotype-phenotype relationships.
- Goldin, Lynn R., Ph.D.
Analytic methods for detecting susceptibility genes for complex diseases by linkage and association methods. Genetic epidemiology of lymphoproliferative cancers.
- Goldstein, Alisa M., Ph.D.
Genetic epidemiology of cancer, integrating epidemiologic, clinical, and molecular approaches. Developing and evaluating methods to examine gene-environment interactions in complex diseases.
- Greene, Mark H., M.D.
Familial/hereditary cancers, genetic determinants of outcomes following cancer treatment, as well as intervention studies (cancer screening, surgical risk reduction and chemoprevention) in genetically at-risk populations, genetic modifiers of cancer risk, and leveraging alert clinical observations into novel etiologic insights.
- Kratz, Christian, M.D.
Childhood cancer predisposition syndromes, inherited bone marrow failure syndromes, familial/hereditary cancers, childhood myelodysplastic syndrome and myeloproliferative disorders, as well as developmental disorders that are caused by germline mutations in cancer-related genes.
- Landi, Maria T., M.D., Ph.D.
Association and linkage approaches in genetic epidemiology of cutaneous malignant melanoma, genetic factors of lung cancer and smoking, health consequences of dioxin exposure.
- Savage, Sharon A., M.D.
Genetic and molecular epidemiology of telomere biology, pediatric cancer etiology, and inherited cancer predisposition syndromes.
- Schiffman, Mark, M.D., M.P.H.
Molecular epidemiology to study the natural history of human papillomavirus infection on the risk of cervical cancer. Applications for cervical cancer prevention.
- Stewart, Douglas, M.D.
Somatic and germline variants increasing tumor risk in neurofibromatosis type 1. Next-generation sequencing of NF1-associated tumors. Characterization and gene identification in novel familial tumor-predisposition syndromes.
- Taylor, Philip R., M.D., Sc.D
Development of prevention strategies for cancers of the upper gastrointestinal tract (esophageal and gastric cancers) using a variety of research approaches (cancer prevention trials, early detection studies, etiologic studies, laboratory-based molecular research, and clinical nutrition studies).
- Tucker, Margaret A., M.D.
Studies of predictors of high cancer risk among populations with specific genetic alterations or families with high rate of cancers. Integration of clinical, epidemiologic, and molecular research.
- Wentzensen, Nicolas, M.D., Ph.D.
Etiology of cervical, ovarian, and endometrial cancer. HPV - related carcinogenesis. Discovery and translation of biomarkers for gynecological cancers. Gene methylation.
- Yang, Rose, Ph.D., M.P.H.
Genetics of familial cutaneous malignant melanoma/dysplastic nevi syndrome and chordoma, and etiologic heterogeneity of breast cancer.