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Principal Investigators

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  • Alter, Blanche P., M.D., M.P.H.
    Study of inherited bone marrow failure syndromes. Using Fanconi's anemia as the prototype for an interdisciplinary approach to elucidate the mechanisms of carcinogenesis in humans.


  • Brown, Kevin, Ph.D.
    Melanoma, genome-wide association studies, familial linkage studies, RNAi, cancer therapeutics.


  • Caporaso, Neil E., M.D.
    Molecular epidemiology of lung and other tobacco-related cancers. Family studies of lympho-proliferative cancers, i.e., chronic lymphocytic leukemia. Pharmacogenetics of genotype-phenotype relationships.


  • Goldin, Lynn R., Ph.D.
    Analytic methods for detecting susceptibility genes for complex diseases by linkage and association methods. Genetic epidemiology of lymphoproliferative cancers.
  • Goldstein, Alisa M., Ph.D.
    Genetic epidemiology of cancer, integrating epidemiologic, clinical, and molecular approaches. Developing and evaluating methods to examine gene-environment interactions in complex diseases.
  • Greene, Mark H., M.D.
    Hereditary cancer syndromes, translational clinical research targeting genetically at-risk populations, and genetic modifiers of risk related to outcomes of cancer therapy.


  • Kratz, Christian, M.D.
    Childhood cancer predisposition syndromes, inherited bone marrow failure syndromes, familial/hereditary cancers, childhood myelodysplastic syndrome and myeloproliferative disorders, as well as developmental disorders that are caused by germline mutations in cancer-related genes.


  • Landi, Maria T., M.D., Ph.D.
    Association and linkage approaches in genetic epidemiology of cutaneous malignant melanoma, genetic factors of lung cancer and smoking, health consequences of dioxin exposure.


  • Savage, Sharon A., M.D.
    Telomere biology and its relationship to cancer etiology and inherited disorders. Studies of genomics, population genetics, and cancer predisposition syndromes. Risk factors for osteosarcoma and other pediatric cancers.
  • Schiffman, Mark, M.D., M.P.H.
    Molecular epidemiology to study the natural history of human papillomavirus infection on the risk of cervical cancer. Applications for cervical cancer prevention.
  • Stewart, Douglas, M.D.
    Somatic and germline variants increasing tumor risk in neurofibromatosis type 1. Next-generation sequencing of NF1-associated tumors. Characterization and gene identification in novel familial tumor-predisposition syndromes.


  • Taylor, Philip R., M.D., Sc.D
    Development of prevention strategies for cancers of the upper gastrointestinal tract (esophageal and gastric cancers) using a variety of research approaches (cancer prevention trials, early detection studies, etiologic studies, laboratory-based molecular research, and clinical nutrition studies).
  • Tucker, Margaret A., M.D.
    Studies of predictors of high cancer risk among populations with specific genetic alterations or families with high rate of cancers. Integration of clinical, epidemiologic, and molecular research.


  • Yang, Rose, Ph.D., M.P.H.
    Identification of susceptibility genes for familial cancers (melanoma, chordoma, nasopharyngeal carcinoma). Assessment of etiologic heterogeneity of breast cancer using molecular approaches.