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Principal Investigators

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Clinical Genetics Branch (CGB)


  • Alter, Blanche P., M.D., M.P.H.
    Study of inherited bone marrow failure syndromes. Using Fanconi's anemia as the prototype for an interdisciplinary approach to elucidate the mechanisms of carcinogenesis in humans.


  • Greene, Mark H., M.D.
    Hereditary cancer syndromes, translational clinical research targeting genetically at-risk populations, and genetic modifiers of risk related to outcomes of cancer therapy.


  • Kratz, Christian, M.D.
    Childhood cancer predisposition syndromes, inherited bone marrow failure syndromes, familial/hereditary cancers, childhood myelodysplastic syndrome and myeloproliferative disorders, as well as developmental disorders that are caused by germline mutations in cancer-related genes.


  • Savage, Sharon A., M.D.
    Telomere biology and its relationship to cancer etiology and inherited disorders. Studies of genomics, population genetics, and cancer predisposition syndromes. Risk factors for osteosarcoma and other pediatric cancers.
  • Schiffman, Mark, M.D., M.P.H.
    Molecular epidemiology to study the natural history of human papillomavirus infection on the risk of cervical cancer. Applications for cervical cancer prevention.
  • Stewart, Douglas, M.D.
    Somatic and germline variants increasing tumor risk in neurofibromatosis type 1. Next-generation sequencing of NF1-associated tumors. Characterization and gene identification in novel familial tumor-predisposition syndromes.