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Discovering the causes of cancer and the means of prevention

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Principal Investigators

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Clinical Genetics Branch (CGB)

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  • Achatz, Maria Isabel, M.D., Ph.D.
    Cancer genetics, inherited cancer predisposition syndromes; Clinical, Molecular and epidemiological characterization on Li-Fraumeni syndrome and Xeroderma Pigmentosum
  • Alter, Blanche P., M.D., M.P.H.
    Study of inherited bone marrow failure syndromes. Using Fanconi's anemia as the prototype for an interdisciplinary approach to elucidate the mechanisms of carcinogenesis in humans.

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  • Gadalla, Shahinaz, Ph.D., M.B.Bch.
    Dr. Gadalla’s research interests focus on the role of genetic factors in cancer etiology, as well as identifying genetic and environmental risk factors among individuals at high risk of developing cancer.
  • Greene, Mark H., M.D.
    Familial/hereditary cancers, genetic determinants of outcomes following cancer treatment, as well as intervention studies (cancer screening, surgical risk reduction and chemoprevention) in genetically at-risk populations, genetic modifiers of cancer risk, and leveraging alert clinical observations into novel etiologic insights.

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  • Savage, Sharon A., M.D.
    Genetic and molecular epidemiology of telomere biology, pediatric cancer etiology, and inherited cancer predisposition syndromes.
  • Schiffman, Mark, M.D., M.P.H.
    Molecular epidemiology to study the natural history of human papillomavirus infection on the risk of cervical cancer. Applications for cervical cancer prevention.
  • Stewart, Douglas, M.D.
    Cancer risk and phenotype in the DICER1 syndrome and neurofibromatosis type 1. Gene identification in familial tumor-predisposition disorders.

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  • Wentzensen, Nicolas, M.D., Ph.D.
    Etiology of cervical, ovarian, and endometrial cancer. HPV - related carcinogenesis. Discovery and translation of biomarkers for gynecological cancers. Gene methylation.