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Principal Investigators

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  • Abnet, Christian C., Ph.D., M.P.H.
    Etiologic studies of esophageal and gastric cancers, with a focus on diet, environmental toxins, and the human microbiome.
  • Achatz, Maria Isabel, M.D., Ph.D.
    Cancer genetics, inherited cancer predisposition syndromes; Clinical, Molecular and epidemiological characterization on Li-Fraumeni syndrome and Xeroderma Pigmentosum
  • Albanes, Demetrius, M.D.
    Nutritional and molecular determinants of prostate, lung, and other cancers. Focus on role of micronutrients, vitamin supplementation, and exposures related to energy balance and anthropometry.
  • Albert, Paul S., Ph.D.
    Complex modeling of correlated outcomes in biomedical sciences, including the analysis of longitudinal data, diagnostic testing, and data from biomarker studies
  • Alter, Blanche P., M.D., M.P.H.
    Study of inherited bone marrow failure syndromes. Using Fanconi's anemia as the prototype for an interdisciplinary approach to elucidate the mechanisms of carcinogenesis in humans.
  • Amundadottir, Laufey, Ph.D.
    gene mapping, functional analyses, pancreatic cancer,
  • Anderson, William F., M.D., M.P.H.
    Cancer surveillance research of breast and other sporadic cancers, supplementing standard descriptive epidemiology with novel biostatistical models and methods to better understand cancer subtypes, trends, and the effects of age-period-cohort events.


  • Beane Freeman, Laura, Ph.D.
    Cancer risks associated with occupational and environmental exposures, including formaldehyde, drinking water contaminants, and those found in agriculture.
  • Berndt, Sonja I., Pharm.D., Ph.D.
    Genetic epidemiology of cancer, particularly prostate cancer, non-Hodgkin lymphoma, and colorectal neoplasia; genetic architecture of anthropometric traits; molecular biomarkers related to cancer.
  • Berrington de González, Amy, D.Phil.
    Risk of radiation-associated tumors after diagnostic and therapeutic medical radiation exposure. Etiology of breast and thyroid cancer.
  • Brinton, Louise A., Ph.D.
    Epidemiology of breast (both female and male), endometrial and ovarian malignancies. Defining the role of both endogenous and exogenous hormones in these cancers and in addressing etiologic heterogeneity within the tumors. Identification of biomarkers (including genetic markers) for these malignancies.
  • Brown, Kevin, Ph.D.
    Melanoma, genome-wide association studies, familial linkage studies, RNAi, cancer therapeutics.


  • Camargo, Maria Constanza, Ph.D.
    Epidemiologic studies of gastric and esophageal cancers that have potential application for screening and prevention.
  • Caporaso, Neil E., M.D.
    Molecular epidemiology of lung and other tobacco-related cancers. Family studies of lympho-proliferative cancers, i.e., chronic lymphocytic leukemia. Pharmacogenetics of genotype-phenotype relationships.
  • Chaturvedi, Anil K., Ph.D.
    Role of HPV in the etiology of head and neck cancers, natural history of head and neck cancer precursors, inflammation and cancer risk, role of inflammation in the etiology of lung cancer and other smoking-associated cancers.
  • Cook, Michael B., Ph.D.
    Molecular epidemiology of esophageal, prostate and testicular cancers. Elucidation of sex differences in cancer incidence.



  • Freedman, Neal D., Ph.D., M.P.H.
    Multidisciplinary studies of liver, esophageal, and gastric cancers; tobacco with cancer.
  • Friesen, Melissa, Ph.D.
    Development and validation of retrospective exposure assessment of occupational risk factors to minimize exposure misclassification in epidemiologic studies of cancer.


  • Gadalla, Shahinaz, Ph.D., M.B.Bch.
    Dr. Gadalla’s research interests focus on the role of genetic factors in cancer etiology, as well as identifying genetic and environmental risk factors among individuals at high risk of developing cancer.
  • Gail, Mitchell H., M.D., Ph.D.
    Studies of breast and gastric cancer etiology and risk assessment. Statistical methods for observational and experimental studies, including design and analysis of genetic epidemiologic studies.
  • Garcia-Closas, Montserrat, M.D., Dr.P.H.
    Use of exposure assessment and biomarkers in large epidemiological studies to investigate of the causes of breast and bladder cancers
  • Gierach, Gretchen L., Ph.D.,
    Etiology of hormonally-related female cancers. Molecular epidemiology of mammographic density and breast cancer.
  • Goldin, Lynn R., Ph.D.
    Analytic methods for detecting susceptibility genes for complex diseases by linkage and association methods. Genetic epidemiology of lymphoproliferative cancers.
  • Goldstein, Alisa M., Ph.D.
    Genetic epidemiology of cancer, integrating epidemiologic, clinical, and molecular approaches. Developing and evaluating methods to examine gene-environment interactions in complex diseases.
  • Graubard, Barry I., Ph.D.
    Use of national surveys and other types of population based-studies for conducting epidemiologic and risk factor surveillance studies related to the incidence of and mortality from cancer. Statistical methods for design and analysis of observational and randomized studies with complex sample designs.
  • Greene, Mark H., M.D.
    Familial/hereditary cancers, genetic determinants of outcomes following cancer treatment, as well as intervention studies (cancer screening, surgical risk reduction and chemoprevention) in genetically at-risk populations, genetic modifiers of cancer risk, and leveraging alert clinical observations into novel etiologic insights.


  • Hildesheim, Allan, Ph.D.
    Exogenous, host, and immunologic factors involved in pathogenesis of DNA- related viruses, including HPV and EBV. Studies in cervical cancer and nasopharyngeal cancer.
  • Hofmann, Jonathan, Ph.D., M.P.H.
    Evaluating the role of agricultural exposures in the etiology of multiple myeloma and other cancers, understanding the biological mechanisms that influence the development and progression of multiple myeloma, and investigating the etiology of renal cell carcinoma
  • Hoover, Robert N., M.D., Sc.D.
    Hormonal carcinogenesis, environmental exposures, occupational exposures, studies of medicinal agents, gene-environment interactions.


  • Katki, Hormuzd A., Ph.D.
    Predicting cervical cancer risk. Estimating absolute risks from studies nested within cohorts. Efficient study designs for comparing diagnostic tests. Methodology for clinical genetics.
  • Kitahara, Cari Meinhold, Ph.D.
    Cancer risks associated with occupational exposure to low-dose radiation from emerging medical practices and procedures, and etiology of radiation-associated cancers, including potential effect modifiers
  • Koshiol, Jill, Ph.D
    Role of immune response in carcinogenesis, with a focus on hepatobiliary and lymphoproliferative cancers.
  • Koutros, Stella, Ph.D.
    Evaluation of occupational exposures as potential risk factors for cancer; exposure assessment and molecular studies within highly exposed populations to identify and clarify the biological mechanisms underlying chemical-induced carcinogenesis; and gene-environment interaction.
  • Kreimer, Aimée R., Ph.D
    Epidemiology of human papillomaviruses (HPV) infection and resultant cancers at multiple anatomic sites, including the oropharynx, cervix, and anus.


  • Lan, Qing, M.D., Ph.D., M.P.H.
    Molecular epidemiology studies of indoor air pollution and lung cancer, molecular epidemiology studies of benzene, trichloroethylene, and formaldehyde, and genetic susceptibility of non-hodgkin lymphoma
  • Landi, Maria T., M.D., Ph.D.
    Association and linkage approaches in genetic epidemiology of cutaneous malignant melanoma, genetic factors of lung cancer and smoking, health consequences of dioxin exposure.
  • Lee, Choonsik, Ph.D.
    Organ radiation dose estimations for diagnostic and therapeutic medical procedures using computer simulations of human anatomy and radiation-generating machines.
  • Linet, Martha S., M.D., M.P.H.
    Hematopoietic, lymphoproliferative, and other cancer risk in adults and children attributable to medical, environmental, and occupational exposures to ionizing and non-ionizing radiation.
  • Little, Mark, D.Phil.
    Low-dose radiation and cancer risk, high-dose radiation and cancer risk, modeling of radio-biological processes.
  • Lubin, Jay H., Ph.D.
    Studies of the carcinogenic effects of radon and other radiation exposures, the assessment of measurement error, and the evaluation of other etiologic factors, including gene-environment interaction.


  • Matthews, Charles, Ph.D.
    Etiologic studies of the role of physical activity and energy balance/obesity in cancer prevention and control, as well as the development of better methods for the assessment of active and sedentary behaviors in population-based research.
  • Mbulaiteye, Sam M., M.D.
    Unraveling the role of infections, immunity, and genetic factors in the etiology of Burkitt lymphoma and Kaposi sarcoma. Both of these malignancies are endemic in Africa and their risk is substantially increased in the setting of HIV/AIDS.
  • McGlynn, Katherine A., Ph.D., M.P.H.
    Molecular epidemiology of primary liver cancer and testicular cancer.
  • Mirabello, Lisa, Ph.D.
    Osteosarcoma etiology and risk factors and carcinogenic HPV genomics
  • Moore, Lee E., Ph.D.
    Use of molecular markers to measure the biological effects of carcinogens in human tissues. Molecular epidemiology of environmental arsenic exposure and of bladder and renal cell carcinoma.
  • Moore, Steven C., Ph.D.
    The role of physical activity and obesity in the development of cancer
  • Morton, Lindsay M., Ph.D.
    Etiology of lymphomas and leukemias. Etiology of second cancers, including treatment, genetic, and lifestyle and environmental risk factors.



  • Pfeiffer, Ruth M., Ph.D.
    Statistical methods for: genetic epidemiology, including power assessment of association studies, family data accounting for ascertainment , DNA pooling for joint genotype estimation, and lab data methods.
  • Purdue, Mark P, Ph.D.
    Molecular investigations into the etiologies of lymphoid malignancies and renal cell carcinoma; exposure to chlorinated solvents and cancer risk.


  • Rabkin, Charles S, M.D.
    Molecular mechanisms of infection-related cancers, pharmacogenomics of iatrogenic malignancies.
  • Rosenberg, Philip S., Ph.D.
    HIV/AIDS natural history. Viruses and cancer, including HCV, SV40, and KSHV. Meta-analysis in genetic epidemiology. Smoothing and nonparametric regression. Cancer susceptibility.
  • Rothman, Nathaniel, M.D., M.P.H., M.H.S.
    Molecular epidemiologic studies of populations exposed to occupational and environmental carcinogens.


  • Sampson, Joshua, Ph.D.
    Statistical methods for identifying biomarkers, such as genes, proteins, and metabolites, associated with cancer risk. Connecting risk factors with etiology of cancer. High dimensional data analysis.
  • Savage, Sharon A., M.D.
    Genetic and molecular epidemiology of telomere biology, pediatric cancer etiology, and inherited cancer predisposition syndromes.
  • Schiffman, Mark, M.D., M.P.H.
    Molecular epidemiology to study the natural history of human papillomavirus infection on the risk of cervical cancer. Applications for cervical cancer prevention.
  • Shi, Jianxin, Ph.D.
    Statistical genetics, with focus on copy number variantion analysis and pathway analysis; statistical analysis of microbiome; analysis of genetic variants related with P53 gene and pathway.
  • Shiels, Meredith, Ph.D.
    Cancer surveillance and data linkage studies; Cancer risk in HIV-infected people; tobacco and cancer
  • Silverman, Debra T., Sc.D., Sc.M.
    Environmental and host determinants of pancreatic cancer, bladder cancer, and carcinogenicity of diesel exhaust.
  • Simon, Steven L., Ph.D.
    Radiation dosimetry and dose reconstruction methods; dose estimation for cohorts exposed to environmental, medical, or occupational radiation; health risks from radiation exposure, doses received from nuclear testing worldwide; radioactivity in man and the environment and quantitative estimation of transfer coefficients; uncertainty analysis of radiation exposure models.
  • Sinha, Rashmi, Ph.D.
    Interdisciplinary studies of diet, genetic susceptibility and cancer etiology. Developing approaches of exposure assessment using questionnaires and biochemical measures.
  • Stewart, Douglas, M.D.
    Cancer risk and phenotype in the DICER1 syndrome and neurofibromatosis type 1. Gene identification in familial tumor-predisposition disorders.
  • Stolzenberg-Solomon, Rachael, Ph.D., M.P.H., R.D.
    Prospective studies of dietary and lifestyle factors, as well as nutritional and molecular biomarkers in relation to primarily gastrointestinal cancers, particularly pancreatic cancer.


  • Taylor, Philip R., M.D., Sc.D
    Development of prevention strategies for cancers of the upper gastrointestinal tract (esophageal and gastric cancers) using a variety of research approaches (cancer prevention trials, early detection studies, etiologic studies, laboratory-based molecular research, and clinical nutrition studies).
  • Trabert, Britton, Ph.D.
    Dr. Trabert’s research interests concentrate on the role of exogenous and endogenous hormones in cancer, and the relationship between chronic inflammation and gynecologic cancers.
  • Tucker, Margaret A., M.D.
    Studies of predictors of high cancer risk among populations with specific genetic alterations or families with high rate of cancers. Integration of clinical, epidemiologic, and molecular research.


  • Ward, Mary H., Ph.D.
    Environmental exposures (drinking water contaminants and pesticides) and exposure assessment using Geographic Information Systems. Etiology of non-Hodgkin's lymphoma and gastric cancer.
  • Wentzensen, Nicolas, M.D., Ph.D.
    Etiology of cervical, ovarian, and endometrial cancer. HPV - related carcinogenesis. Discovery and translation of biomarkers for gynecological cancers. Gene methylation.


  • Yang, Rose, Ph.D., M.P.H.
    Genetics of familial cutaneous malignant melanoma/dysplastic nevi syndrome and chordoma, and etiologic heterogeneity of breast cancer.
  • Yu, Kai, Ph.D.
    Statistical methods for genetic epidemiologic studies. Tree-based modeling for high dimensional data. Population genetics


  • Zahm, Shelia H., Sc.D.
    Research interests include pesticides and cancer, the etiology of non-Hodgkin's lymphoma, and occupational cancer among women.
  • Zhu, Bin, Ph.D.
    Developing and applying novel statistical methods to increase understanding of biological mechanisms underlying complex diseases, and studying the pattern and determinants of disease in human populations.
  • Ziegler, Regina G., Ph.D., M.P.H.
    Research on diet, nutrition, and cancer. The role of vegetables, fruits, and micronutrients in the etiology of cancer.