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Discovering the causes of cancer and the means of prevention

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Title: Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention.
Authors: Karimi P,  Islami F,  Anandasabapathy S,  Freedman ND,  Kamangar F
Journal: Cancer Epidemiol Biomarkers Prev
Date: 2014 May
Branches: MEB
PubMed ID: 24618998
PMC ID: PMC4019373
Abstract: Less than a century ago, gastric cancer was the most common cancer in the United States and perhaps throughout the world. Despite its worldwide decline in incidence over the past century, gastric cancer remains a major killer across the globe. This article reviews the epidemiology, screening, and prevention of gastric cancer. We first discuss the descriptive epidemiology of gastric cancer, including its incidence, survival, mortality, and trends over time. Next, we characterize the risk factors for gastric cancer, both environmental and genetic. Serologic markers and histological precursor lesions of gastric cancer and early detection of gastric cancer using these markers are reviewed. Finally, we discuss prevention strategies and provide suggestions for further research.