Skip to Content
Discovering the causes of cancer and the means of prevention

Publications Search - Abstract View

Title: Gliomas presenting after age 10 in individuals with neurofibromatosis type 1 (NF1).
Authors: Gutmann DH,  Rasmussen SA,  Wolkenstein P,  MacCollin MM,  Guha A,  Inskip PD,  North KN,  Poyhonen M,  Birch PH,  Friedman JM
Journal: Neurology
Date: 2002 Sep 10
Branches: REB
PubMed ID: 12221173
PMC ID: not available
Abstract: Children with neurofibromatosis 1 (NF1) often develop low-grade gliomas, but brain tumors are infrequently encountered in adults with NF1. The authors present evidence from two clinical series, one including patients known to have NF1 and another focusing on adults with new onset brain tumors, that suggests an association between NF1 and symptomatic gliomas in older individuals. They also summarize the clinical data on 17 adolescents or adults with NF1 and symptomatic gliomas. The findings suggest that individuals with NF1 are at increased risk of developing gliomas throughout their lives.