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Title: Does nondifferential misclassification of exposure always bias a true effect toward the null value - reply
Authors: Dosemeci M,  Wacholder S,  Lubin JH
Journal: Am J Epidemiol
Date: 1991 Aug 15
Branches: BB, OEEB
PubMed ID: 2403115
PMC ID: not available
Abstract: The authors present some examples to demonstrate that in certain nondifferential misclassification conditions with polychotomous exposure variables, estimates of odds ratios for categories at intermediate level of risk can be biased away from the null or can change direction. In addition, the authors present two examples to demonstrate that the slope of the dose-response trend for the true distributions can change direction, creating a false inverse trend, even if the misclassification is nondifferential.