Atlas of Cancer Mortality

Results -- Geographic Patterns for Liver Cancer

Rates were elevated in many areas across the south-central and southwestern states among whites and were generally low in northern areas. Little geographic variation was evident in blacks, whose rates have been higher than those among whites. Liver cancer is particularly subject to misspecification on death certificates,50 but it is unclear whether diagnostic and reporting practices have varied geographically. In the SEER data, liver cancer incidence rates are higher among Hispanic than non-Hispanic whites, 37 which probably contributes to the excess mortality in the southwestern states. Further work is needed to clarify the role of hepatitis B and C infection, as well as that of alcohol consumption, in the ethnic and geographic patterns of liver cancer. 51

References
37. Miller BA, Kolonel LN, Bernstein L, Young JL Jr, Swanson GM, West DW, Key CR, Liff JM, Glover CS, Alexander GA, editors. Racial/ethnic patterns of cancer in the United States 1988-1992. Bethesda, MD: National Cancer Institute; 1996. NIH Publ. No. 96-4104.
50. Percy C, Ries LG, Van Holten VD. The accuracy of liver cancer as the underlying cause of death on death certificates. Public Health Rep 1990;105:361-7.
51. London WT, McGlynn KA. Liver cancer. In: Schottenfeld D, Fraumeni JF Jr, editors. Cancer epidemiology and prevention. 2nd ed. New York: Oxford University Press; 1996. p. 772-93.

Suggested Citation

Devesa SS, Grauman DG, Blot WJ, Pennello G, Hoover RN, Fraumeni JF Jr. Atlas of cancer mortality in the United States, 1950-94. Washington, DC: US Govt Print Off; 1999 [NIH Publ No. (NIH) 99-4564].
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