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Title: Identification of a new prostate cancer susceptibility locus on chromosome 8q24.
Authors: Yeager M,  Chatterjee N,  Ciampa J,  Jacobs KB,  Gonzalez-Bosquet J,  Hayes RB,  Kraft P,  Wacholder S,  Orr N,  Berndt S,  Yu K,  Hutchinson A,  Wang Z,  Amundadottir L,  Feigelson HS,  Thun MJ,  Diver WR,  Albanes D,  Virtamo J,  Weinstein S,  Schumacher FR,  Cancel-Tassin G,  Cussenot O,  Valeri A,  Andriole GL,  Crawford ED,  Haiman CA,  Henderson B,  Kolonel L,  Le Marchand L,  Siddiq A,  Riboli E,  Key TJ,  Kaaks R,  Isaacs W,  Isaacs S,  Wiley KE,  Gronberg H,  Wiklund F,  Stattin P,  Xu J,  Zheng SL,  Sun J,  Vatten LJ,  Hveem K,  Kumle M,  Tucker M,  Gerhard DS,  Hoover RN,  Fraumeni JF,  Hunter DJ,  Thomas G,  Chanock SJ
Journal: Nat Genet
Date: 2009 Oct
Branches: BB, CGR, EBP, HGP, LTG, NEB, OD, OEEB
PubMed ID: 19767755
PMC ID: PMC3430510
Abstract: We report a genome-wide association study in 10,286 cases and 9,135 controls of European ancestry in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. We identify a new association with prostate cancer risk on chromosome 8q24 (rs620861, P = 1.3 x 10(-10), heterozygote OR = 1.17, 95% CI 1.10-1.24; homozygote OR = 1.33, 95% CI 1.21-1.45). This defines a new locus associated with prostate cancer susceptibility on 8q24.