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Title: Occupational risk of lung cancer among lifetime non-smoking women in Shanghai, China.
Authors: Pronk A,  Coble J,  Ji BT,  Shu XO,  Rothman N,  Yang G,  Gao YT,  Zheng W,  Chow WH
Journal: Occup Environ Med
Date: 2009 Oct
Branches: OEEB
PubMed ID: 19625285
PMC ID: PMC3007593
Abstract: OBJECTIVES: Occupational lung carcinogens have been primarily studied in men. The aim of this study was to investigate occupational lung cancer risk in a cohort of Chinese non-smoking women. METHODS: In 1996-2000, 71 067 non-smoking women who had held a job outside the home were interviewed for the prospective Shanghai Women's Health Study in China. Exposure to lung carcinogens was assessed by matching occupation and industry titles from lifetime occupational histories with lists of jobs identified by the International Agency for Research on Cancer to have potential exposure to: (1) known (A-list); or (2) suspected (B-list) carcinogens. In addition, similar occupational titles were grouped independent of the a priori defined lists. Relative risks (RRs) were calculated using Cox proportional hazards regression. RESULTS: During follow-up through 2005, 219 incident lung cancer cases were diagnosed. Jobs on the A-list and B-list were held by 0.8-6.7% and 2.7-9.4% of the cohort, respectively. Overall, ever holding any job on the A-list or B-list was not associated with lung cancer incidence. Indications of excess risk were found for two subgroups: painters (A-list) and rubber workers (B-list) (RR = 2.0 and 1.7, respectively, p