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||Switch from cytology-based to human papillomavirus test-based cervical screening: implications for colposcopy.
||Porras C, Wentzensen N, Rodríguez AC, Morales J, Burk RD, Alfaro M, Hutchinson M, Herrero R, Hildesheim A, Sherman ME, Wacholder S, Solomon D, Schiffman M
||Int J Cancer
||2012 Apr 15
||BB, CGB, HREB, IIB
||Human papillomavirus (HPV) testing is more sensitive than cytology; some cervical cancer prevention programs will switch from cytology to carcinogenic HPV test-based screening. The objective of our study is to evaluate the clinical implications of a switch to HPV test-based screening on performance and workload of colposcopy. Women in the population-based, 7-year Guanacaste cohort study were screened at enrollment using cytology. We also took another specimen for HPV DNA testing and collected magnified cervical photographic images (cervigrams). A final case diagnosis (≥cervical intraepithelial neoplasia [CIN] grade 3, CIN2,