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Title: Switch from cytology-based to human papillomavirus test-based cervical screening: implications for colposcopy.
Authors: Porras C,  Wentzensen N,  Rodríguez AC,  Morales J,  Burk RD,  Alfaro M,  Hutchinson M,  Herrero R,  Hildesheim A,  Sherman ME,  Wacholder S,  Solomon D,  Schiffman M
Journal: Int J Cancer
Date: 2012 Apr 15
Branches: BB, CGB, HREB, IIB
PubMed ID: 21607948
PMC ID: PMC3162132
Abstract: Human papillomavirus (HPV) testing is more sensitive than cytology; some cervical cancer prevention programs will switch from cytology to carcinogenic HPV test-based screening. The objective of our study is to evaluate the clinical implications of a switch to HPV test-based screening on performance and workload of colposcopy. Women in the population-based, 7-year Guanacaste cohort study were screened at enrollment using cytology. We also took another specimen for HPV DNA testing and collected magnified cervical photographic images (cervigrams). A final case diagnosis (≥cervical intraepithelial neoplasia [CIN] grade 3, CIN2,