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Title: Cancer sequencing gets a little more personal.
Authors: Prokunina-Olsson L,  Chanock SJ
Journal: Sci Transl Med
Date: 2010 Feb 24
Branches: CGR, LTG
PubMed ID: 20371489
PMC ID: not available
Abstract: In this Perspective, we discuss a paper in this issue of Science Translational Medicine, in which Leary and colleagues present a new method based on massive, parallel, and near-complete sequencing of individual tumor genomes. Their findings support the notion that cancer genomes house a spectrum of genetic alterations, many of which are unique to the individual tumor. More validation and a reduction in cost are required for this approach to become common in clinics.