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Title: Retinoblastoma incidence and sunlight exposure.
Authors: Jemal A,  Devesa SS,  Fears TR,  Fraumeni JF Jr
Journal: Br J Cancer
Date: 2000 Jun
Branches: BB, OD
PubMed ID: 10839306
PMC ID: PMC2363228
Abstract: To evaluate positive findings from an earlier report, we studied the relation between retinoblastoma incidence and ultraviolet (UV-B) radiation levels in the Surveillance, Epidemiology, and End Results (SEER) programme areas of the USA using weighted regression, as well as in international data after adjusting for race, economic development, and climate. The association was not statistically significant within the USA (P > 0.20). At an international level, the relation was significant overall and after adjusting for economic development, but it was not significant after adjusting for race and tropical climate, suggesting that environmental factors other than UV-B may be responsible for the geographic patterns of retinoblastoma.