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Discovering the causes of cancer and the means of prevention

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Title: Bacillus Calmette-Guérin vaccination and cancer prevention: a critical review of the human experience.
Authors: Hoover RN
Journal: Cancer Res
Date: 1976 Feb
Branches: EBP
PubMed ID: 1253150
PMC ID: not available
Abstract: Published studies of the cancer experiences of children vaccinated with Bacillus Calmette-Guérin in antituberculosis programs were reviewed and the strengths and weaknesses of each evaluated. There is little evidence that vaccination outside of the neonatal period is effective. If there is an effect of neonatal vaccination, it must convey only a small amount of "protection." Follow-up studies adequate to assess the long-term effects of such vaccination, particularly the risk of lymphoma, have not been done, and recent evidence indicates that such evaluation is warranted.