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Title: Precursor lesions in familial melanoma.
Authors: Greene MH,  Reimer RR,  Clark WH Jr,  Mastrangelo MJ
Journal: Semin Oncol
Date: 1978 Mar
Branches: CGB
PubMed ID: 635599
PMC ID: not available
Abstract: Familial occurrences of malignant melanoma may be related to an inherited syndrome of precursor cutaneous lesions with distinct clinical and histologic features. Recognition of the syndrome in the relatives of melanoma patients identifies a subset of family members at high risk for melanoma, facilitating their early diagnosis and treatment. Further studies of these families may provide insight into the biology of malignant melanoma and the pathophysiology of malignant transformation in benign nevi.