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Title: High-risk oral human papillomavirus load in the US population, National Health and Nutrition Examination Survey 2009-2010.
Authors: Chaturvedi AK,  Graubard BI,  Pickard RK,  Xiao W,  Gillison ML
Journal: J Infect Dis
Date: 2014 Aug 1
Branches: BB, IIB
PubMed ID: 24625808
PMC ID: PMC4110460
Abstract: We investigated the association of demographic and behavioral factors with oral human papillomavirus (HPV) load for 18 high-risk types among 211 individuals with prevalent high-risk HPV within the National Health and Nutrition Examination Survey 2009-2010. Factors independently associated with HPV load above the median included older age (odds ratio, 1.04 per year increase [95% confidence interval, 1.01-1.07]; P = .004) and intensity of current smoking (P for trend <.001). A marginally greater percentage of men than women had an HPV load above the median (55.7% vs 32.8%; P = .069), and HPV load increased marginally with increasing alcohol use (P for trend = .062). In conclusion, older age and current smoking are associated with a high oral load of high-risk HPV types among individuals with a prevalent infection.