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Title: A twist on admixture mapping.
Authors: Chanock SJ
Journal: Nat Genet
Date: 2011 Mar
Branches: CGR, LTG
PubMed ID: 21350496
PMC ID: not available
Abstract: A new study uses genome-wide SNP genotypes to identify a subset of children undergoing therapy for acute lymphoblastic leukemia that are at increased risk for relapse. Borrowing from the classical approach of admixture mapping, the work shows how genome-wide assessment of genetic ancestry can be used as a biomarker for disease outcome.