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Title: Telomeres in molecular epidemiology studies.
Authors: Bodelon C,  Savage SA,  Gadalla SM
Journal: Prog Mol Biol Transl Sci
Date: 2014
Branches: CGB, HREB
PubMed ID: 24993700
PMC ID: not available
Abstract: Telomeres are long nucleotide repeats and protein complexes at the ends of chromosomes that are essential for maintaining chromosomal stability. They shorten with each cell division, and therefore, telomere length is a marker for cellular aging and senescence. Epidemiological research of telomeres investigates the role that these genetic structures have in disease risk and mortality in human populations. This chapter provides an overview of the current telomere epidemiology research and discusses approaches taken in these investigations. We also highlight important methodological considerations that may affect data interpretation.